Visiting Scholars

Wan You



Postdoctoral Fellows

Karine Bon

William R. Lariviere
Kumar V.S. Nemmani
Michael LaCroix-Fralish



Graduate Students

Sonya Wilson

Elissa Chesler

Shad B. Smith


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Contact
William Lariviere, Ph.D. (McGill University)
1999-2001

Genetic Correlation of Pain



Currently an Asst. Prof. at the University of Pittsburgh

lariwr@upmc.edu

  • Lariviere, W.R., Chesler, E.J., and Mogil, J.S.  Transgenic studies of pain and analgesia: mutation or background genotype?  J. Pharmacol. Exp. Ther., 297:467-473, 2001.
  • Lariviere, W.R., Wilson, S.G., Laughlin, T.M., Kokayeff, A., West, E.E., Adhikari, S.M., Wan, Y., and Mogil, J.S.  Heritability of nociception. III. Genetic relationships among commonly used assays of nociception and hypersensitivity.  Pain, 97:75-86, 2002.
  • Chesler, E.J., Wilson, S.G., Lariviere, W.R., Rodriguez-Zas, S.L., and Mogil, J.S.  Influences of laboratory environment on behavior.  Nature Neurosci., 5:1101-1102, 2002.
  • Chesler, E.J., Wilson, S.G., Lariviere, W.R., Rodriguez-Zas, S.L., and Mogil, J.S.  Identification and ranking of genetic and laboratory environmental factors influencing a behavioral trait, thermal nociception, via computational analysis of a large data archive.  Neurosci. Biobehav. Rev., 26:907-923, 2002.
  • Mogil, J.S., Wilson, S.G....Lariviere, W.R....and Fillingim, R.B.  The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans.  Proc. Natl. Acad. Sci. USA, 100:4867-4872, 2003.
  • Wilson, S.G., Bryant, C.D., Lariviere, W.R., Olsen, M.S., Giles, B.E., Chesler, E.J., and Mogil, J.S.  The heritability of antinociception II: pharmacogenetic mediation of three over-the-counter analgesics in mice.  J. Pharmacol. Exp. Ther., 305:755-764, 2003.
  • Lariviere, W.R. and Mogil, J.S.  Genetic basis of pain induction and modulation. In: Chen, J., Chen, A.C.N., Han, J.-S. and Willis, W.D. (Eds.) Experimental Pathological Pain: From Molecules to Brain Functions.  Science Press, Beijing, 2003.
  • Chesler, E.J., Ritchie, J., Kokayeff, A., Lariviere, W.R., Wilson, S.G., and Mogil, J.S.  Genotype-dependence of gabapentin and pregabalin sensitivity: the pharmacogenetic mediation of analgesia is specific to the type of pain being inhibited.  Pain, 106:325-335, 2003.
  • Lariviere, W.J. and Mogil, J.S.  The genetics of pain and analgesia in laboratory animals.  In: Szallasi, A. (Ed.) Methods in Molecular Biology--Analgesia.  Humana Press, Totowa, NJ, in press.